Chemokine (C-X-C motif) Receptor 2

Chemokine (C-X-C motif) Receptor 2

ExpressMAX™ Expression-ready Human GPCR ORF Clones

Product Overview:

It is a receptor for Interleukin 8 (IL8). It binds to IL8 with high affinity and transduces the signal through a G-protein activated second messenger system. It also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity and has been shown to be a major component required for serum-dependent melanoma cell growth. It mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor.

Quote request

Availability: In stock! Ready-to-ship immediately

Catalog Numbers, Sizes & Prices

Cat. No. Size Price
G0536-A 15 µL (15 assays) 148 €
G0536-B 15 µL (15 assays) 897 €
G0536-Plus 15 µL + 0.2 mL (15 assays) 958 €

Press here to learn the difference between this three products.

 

Different specifications, sizes or Bulk Orders? please visit Custom Solutions or OEM partnerships.

Note: Prices may vary between countries, because additional cost may be applied due taxes, shipments or Custom fees.

Advantages & Features

  • Native structure.
  • Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables.
  • Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry.
  • Wide spectrum: of strong constitutive promoters.
  • Complete solution: it contains all necessary elements for maximum receptor expression.
  • Ready-to-use solution: avoids cloning steps, DNA ready to transfect.
  • Easy protocol and detection: the whole procedure is simple, with minimal handling.
  • Neomycin resistance.
  • Ampicillin bacterial selection.

Specifications

  • Plasmid size: 7062 pb
  • Promoter: PEF1α
  • ORF Sequence (GenBank based): NM_001557
  • Protein Sequence (SwissProt): P25025
  • Bacterial Selection Antibiotics: Ampicillin
  • Mammalian Selection Antibiotic: Neomycin
  • Alternative names: CD182, IL8R2 or IL8RB

Includes

Includes for 15 μg:

ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL)

 

Mammalian Transfection Kits (Cat. No. -PLUS):
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL)
– 0.2 mL CANFAST™ Transfection Reagent

(15 µg = 15 assays)

Download documentation

Brochure

Applications

  • Functional assays, as protein immobilization, cellular localization and other functional assays.
  • High-throughput and large scale protein production and purification.
  • Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

Quality Control

The quantity and quality of purified DNA is checked by:

  • Ratio 260/ 280.
  • Agarose gel electrophoresis.
  • Digestion with restriction endonucleases.

Storage, Shipping & Guarantee​

  • Shipped in: Dry Ice.
  • Storage: ExpressMAX™ GPCR ORF Clones (-20 ºC) and CANFAST™ (4 ºC).
  • Shelf Life: 24 months from the date of purchase, if it is properly stored.

Safety Statements

This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals. For more info, please check its Material Safety Data Sheet available in this website.

Current Promotions


Citations Reward Program, get 50€ Amazon gift card Learn more Here


Lab Start-Up Program for new labs/companies Learn more Here


Bulk & Volume discounts for larger quantities Learn more Here

Frequently asked questions

Do you have any question? Please visit our FAQs section GO

Customers Review