Adenosine A3 Receptor

Adenosine A3 Receptor

ExpressMAX™ Expression-ready Human GPCR ORF Clones

Product Overview:

Adenosine A3 (ADORA3) belongs to the family of adenosine Receptors, which are GPCRs that mediates a sustained cardioprotective function during cardiac ischemia. Also it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects and it may mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms (1, 2 and 3) have been found for the gene.

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Availability: In stock! Ready-to-ship immediately

Catalog Numbers, Sizes & Prices

Cat. No. Size Price
G0501-B Bacterial Stock 289 €
G0501-Plus 15 µL (12-well plate) + 0.2 mL 667 €

Press here to learn the difference between this three products.

 

Different specifications, sizes or Bulk Orders? please visit Custom Solutions or OEM partnerships.

Note: Prices may vary between countries, because additional cost may be applied due taxes, shipments or Custom fees.

Advantages & Features

  • Native structure.
  • Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables.
  • Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry.
  • Wide spectrum: of strong constitutive promoters.
  • Complete solution: it contains all necessary elements for maximum receptor expression.
  • Ready-to-use solution: avoids cloning steps, DNA ready to transfect.
  • Easy protocol and detection: the whole procedure is simple, with minimal handling.
  • Neomycin resistance.
  • Ampicillin bacterial selection.

Specifications

  • Plasmid  size: 6596 bp
  • Promoter: pCMV
  • ORF Sequence (GenBank based): NM_000677.3
  • Protein Sequence (SwissProt): P33765
  • Bacterial Selection Antibiotics:  Ampicillin
  • Mammalian Selection Antibiotic: Neomycin
  • Alternative names: A3AR

Includes

Includes:

 

ExpressMAX™ GPCR ORF Clones (Cat. No. – B)

– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.

 

Mammalian Transfection Kits (Cat. No. – PLUS):
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0.2 mL CANFAST™ Transfection Reagent.

Download documentation

Data Sheet
Brochure

Applications

  • Functional assays, as protein immobilization, cellular localization and other functional assays.
  • High-throughput and large scale protein production and purification.
  • Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

Quality Control

The quantity and quality of purified DNA is checked by:

  • Ratio 260/ 280.
  • Agarose gel electrophoresis.
  • Digestion with restriction endonucleases.

Storage, Shipping & Guarantee​

  • Shipped in: Dry Ice.
  • Storage: ExpressMAX™ GPCR ORF Clones (-20 ºC) and CANFAST™ (4 ºC).
  • Shelf Life: 24 months from the date of purchase, if it is properly stored.

Safety Statements

This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals. For more info, please check its Material Safety Data Sheet available in this website.

Frequently asked questions

Do you have any question? Please visit our FAQs section GO

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