Chemokine (C-C motif) Receptor-like 2
ExpressMAX™ Expression-ready Human GPCR ORF Clones
Product Overview:
It is a Chemokine Receptor Like Protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation.
The gene is expressed at high levels in primary neutrophils and primary monocytes and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. This gene is mapped to the region where the chemokine receptor gene cluster is located.
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Catalog Numbers, Sizes & Prices
| Cat. No. | Size | Price |
| G0532-A | 15 µL (15 assays) | 148 € |
| G0532-B | 15 µL (15 assays) | 298 € |
| G0532-Plus | 15 µL + 0.2 mL (15 assays) | 688 € |
Press here to learn the difference between this three products.
Different specifications, sizes or Bulk Orders? please visit Custom Solutions or OEM partnerships.
Note: Prices may vary between countries, because additional cost may be applied due taxes, shipments or Custom fees.
Advantages & Features
- Native structure.
- Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables.
- Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry.
- Wide spectrum: of strong constitutive promoters.
- Complete solution: it contains all necessary elements for maximum receptor expression.
- Ready-to-use solution: avoids cloning steps, DNA ready to transfect.
- Easy protocol and detection: the whole procedure is simple, with minimal handling.
- Neomycin resistance.
- Ampicillin bacterial selection.
Specifications
- Plasmid size: 7023 pb
- Promoter: PEF1α
- ORF Sequence (GenBank based): NM_003965
- Protein Sequence (SwissProt): O00421
- Bacterial Selection Antibiotics: Ampicillin
- Mammalian Selection Antibiotic: Neomycin
- Alternative names: HCR, CKRX, CRAM or ACKR5
Includes
Includes for 15 μg:
ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL)
Mammalian Transfection Kits (Cat. No. -PLUS):
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL)
– 0.2 mL CANFAST™ Transfection Reagent
(15 µg = 15 assays)
Download documentation
BrochureApplications
- Functional assays, as protein immobilization, cellular localization and other functional assays.
- High-throughput and large scale protein production and purification.
- Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).
Quality Control
The quantity and quality of purified DNA is checked by:
- Ratio 260/ 280.
- Agarose gel electrophoresis.
- Digestion with restriction endonucleases.
Storage, Shipping & Guarantee
- Shipped in: Dry Ice.
- Storage: ExpressMAX™ GPCR ORF Clones (-20 ºC) and CANFAST™ (4 ºC).
- Shelf Life: 24 months from the date of purchase, if it is properly stored.
Safety Statements
This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals. For more info, please check its Material Safety Data Sheet available in this website.
