Human TNFa (Tumor Necrosis Factor), 6xHis tag

Human TNFa (Tumor Necrosis Factor), 6xHis tag

High quality Recombinant Protein with proven performance in ELISA, WB, Ab Production or Protein array

Product Overview:

Multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation.

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Availability: In stock! Ready-to-ship immediately

Catalog Numbers, Sizes & Prices

Cat. No. Size Price
PR0551 20 μg 161 €
PR0552 50 μg 220 €
PR0553 100 μg 328 €

Different specifications, sizes or Bulk Orders? please visit Custom Solutions or OEM partnerships.

Note: Prices may vary between countries, because additional cost may be applied due taxes, shipments or Custom fees.

Advantages & Features

  • Highest purity: free of interferences from other proteins or contaminants.
  • Convenient: available in different sizes and tags.

Specifications

  • Source: E. coli.
  • AA Sequence:  77-233 aa (partial, without signal peptide).
  • Predicted MW: 18.4 kDa
  • Purity:  >90% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-TNFa (WB).
  • Tag: 6xHis tag.
  • Buffer: 20mM Sodium Phosphate, 0.5M NaCl, pH 7.4. No preservatives added.
  • Biological activity: Not tested.
  • Synonyms:  DIF, TNFA, TNFSF2, Cachectin; APC1 protein; TNF, macrophage-derived; Tumor necrosis factor ligand superfamily member 2.
  • Official Symbol:  TNFa.
  • Specie:  Homo sapiens.
  • GenBank accession number:  NM_000594.3
  • NCBI Protein RefSeq:  NP_000585.2
  • Protein Family: Cytokine.

Includes

Includes for 50 μg:

– 50 μg Recombinant Protein

– Dry ice

Download documentation

Data Sheet
Brochure

Applications

  • ELISA.
  • Western Blot.
  • Antibody Production.
  • Protein array.

Quality Control

  • 15% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-TNFa (WB) and peptide fingerprinting by MALDI-TOF mass spectrometry.

Advice

  • Recommendations: Prior to reconstitution, store the lyophilized protein at 2−8 ºC. After reconstitution, store in working aliquots at −80 ºC.

Storage, Shipping & Guarantee​

  • Shipped in: Lyophilized at Ambient Temperature.
  • Storage: Room Temperature.
  • Guaranteed: All components are stable for 1 year of receipt,  if stored properly.

Safety Statements

This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals. For more info, please check its Material Safety Data Sheet available in this website.

Frequently asked questions

Do you have any question? Please visit our FAQs section GO

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